LONDON — Campaigners fighting British government plans to expand Heathrow Airport have lost a challenge in one of the country’s highest courts.A coalition of local councils, environmentalists and London residents claim the government has failed to properly address the impact on air quality, climate change, noise and congestion that adding a third runway would entail. London Mayor Sadiq Khan has also backed the lawsuit.The environmental group Greenpeace says that while the campaigners may have lost this judgment, the government is losing the argument on whether such expansion is “morally justifiable.”Parliament approved plans last year for the third runway, backing what the government described as the most important transportation project in a generation.Prime Minister Theresa May has said the expansion will boost economic growth.The Associated Press
15 July 2009A new United Nations Children’s Fund (UNICEF) kit – the first of its kind in the humanitarian community – seeks to help young children who have been uprooted from their homes or affected by war and natural disasters regain a sense of normalcy. Launched by UNICEF Executive Director Ann M. Veneman in Geneva today, each Early Childhood Development Kit, which costs $230, can be used by some 50 children up to six years of age.They contain 37 items – including dominos, colouring pencils, construction blocks, hand puppets and memory games – that encourage playing, drawing, story-telling and numeracy.According to an agency press release, early childhood is the most critical period for brain development, with young children especially vulnerable to the stresses of war and disasters, such as hurricanes, floods and earthquakes.The kit was created after UNICEF staff and partner organizations responding to emergencies identified a need for special materials to help young children.Before its launch today, the kit was tested in seven countries – Chad, Liberia, the Republic of Congo, Jamaica, Guyana, Maldives and Iraq.The new kit complements UNICEF’s “school-in-a-box,” of which 600,000 have been distributed during emergencies to date.
The mission, led by Bacre Waly Ndiaye, Director of the UN Human Rights Office in New York, has started in neighbouring Chad, where tens of thousands of Sudanese have fled over the past year to escape the violence.The team will interview Sudanese refugees taking shelter there before travelling to Darfur itself to assess the situation. The mission is expected to last about 10 days, a UN spokesman told reporters today in New York.Bertrand Ramcharan, the Acting High Commissioner for Human Rights, set up the mission to investigate reports that systematic human rights abuses are occurring against civilians in Darfur.Last Friday Jan Egeland, the Under-Secretary-General for Humanitarian Affairs and Emergency Relief Coordinator, said a coordinated, “scorched earth” campaign of ethnic cleansing was taking place in Darfur, which is in Sudan’s west.Mr. Egeland said the region’s black African population, especially the Fur, Zaghawas and Massalit ethnic communities, were being forcibly driven away from the area by militia groups allied to the Sudanese Government.Militia groups, the Sudanese Government and rebel groups have been fighting in Darfur for just over a year.As the fact-finding mission begins work, the UN Office in Sudan is reporting that conditions in Darfur have worsened in some areas, a UN spokesman said.He said outbreaks of communicable diseases, such as measles, are increasing because of the rising number of internally displaced people moving to relatively urban areas in Darfur. Some 200 cases of measles have been confirmed in one camp alone.Humanitarian agencies say they cannot provide enough food, clean water, shelter and health care to internally displaced Sudanese because of the lack of security in Darfur.
AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email Orlando’s WKMG issues message during game explaining why it has to air struggling Jaguars ORLANDO, Fla. – An Orlando television station has issued an on-air explanation for why it’s airing the struggling Jacksonville Jaguars while many NFL fans probably would have preferred seeing the Denver Broncos-New York Giants game, a possible Super Bowl preview featuring the Peyton and Eli Manning.WKMG TV issued the scrolled message on Sunday. It read that NFL policy states the station must carry all Jags away games. At the end the message said: “We apologize for any inconvenience.”Viewers then took to Twitter to remark on what many saw as an apology from the station.But WKMG Vice-President and General Manager Skip Valet says the arrangement is nothing new. He says for nearly two decades Orlando has been designated the secondary Jaguars market and has carried all the away games. As he put it: “I know it’s frustrating, but as a CBS station in this market you have to carry the away games.”Jaguars scored an NFL-low 2 points last week and are coming off the worst season in franchise history. They have missed the playoffs 11 of the last 13 years. by The Associated Press Posted Sep 15, 2013 4:08 pm MDT
4.Flensburg-H.7304196:1906 Pick Szegedskjern handbold After half of the road to the end of EHF Champions League Preliminary Round, it is clear that in Group B Paris Saint Germain Handball and MOL Pick Szeged are the only candidates for the place No.1 and direct placement at quarter-finals.MOL Pick Szeged won in Skjern 29:26.Skjern – Szeged 26-29 (15-14)Skjern: Anders Eggert 6, Thomas Mogensen 5, Christoffer Mikkelsen 5, Eivind Tangen 5, Jesper Konradsson 2, Kasper Søndergaard 1, Sebastian Augustinussen 1, Jonathan Stenbäcken 1.Szeged: Mario Sostaric 6, Joan Cañellas 5, Jorge Maqueda 3, Stefan Sigurmannsson 3, Bence Banhidi 3, Jonas Källman 2, Zsolt Balogh 2, Dmitrii Zhitnikov 2, Dean Bombac 1, Matej Gaber 1, Richard Bodo 1.STANDINGS: 8.Motor Zaporozhye7115210:2253 7.Celje7205176:2034 3.Nantes7313219:2037 2.Szeged7601209:19312 1.Paris SG7700223:18814 6.PPD Zagreb7214177:1965 5.Skjern7214194:2065 ← Previous Story Powerful Barca win in Skopje! Next Story → Rogerio Moraes to solve knee problems
THREE OF THE nine people arrested in relation to the murder of British soldier Lee Rigby last week have been released on bail, Scotland Yard said this morning.They had been arrested in south London on Saturday on suspicion of conspiracy to murder. Police said the men are expected to return to a city station, pending further enquiries.The two suspected killers, Michael Adebolajo, 28, and Michael Adebowale, 22, remain under armed guard in separate hospitals after being shot by police at the scene last Wednesday.A third man, arrested yesterday, is also still in custody at a south London police station.One other man and two women were also arrested as part of the investigation. The two women were released without charge, while the 29-year-old man was bailed to return on suspicion of conspiracy to murder.In a statement this morning, the Metropolitan Police Service said it was working “tirelessly and painstakingly to uncover the full circumstances relating to the murder”. Its Counter Terrorism Command is being assisted by national counter-terrorism officers and the Security Service.Lee Rigby, a 25-year-old father, husband and serving soldier, was killed in a brutal attack in broad daylight on 22 May.The gruesome nature of the murder — some witnesses say the men tried to decapitate their victim — their politically-fuelled rants to passers-by, and their apparent desire for publicity all point to militant Islamist extremism, experts say.-Additional reporting by AFPEarlier: Sixth man arrested in connection to Lee Rigby murderMore: French soldier stabbed in neck outside ParisRelated: Murder of London soldier raises fears of ‘lone wolf’ attacks
Long protected by the non-practice of security by obscurity, Apple users recently joined the unfortunate, unwary legions targeted by fakeAV malware. As cybercriminals had previously discovered on Windows, it’s far easier to trick users into installing a malicious application than wasting precious effort coding a more complex virus or worm.While some pundits scoffed at the latest round of “Mac malware is finally here” blog posts, the Mac Defender rogue and its variants have become very serious very quickly. Ed Bott recently spoke with an anonymous AppleCare support rep who told him what started as a few calls intermingled with the usual case load has swelled — now accounting for about 50% of all calls.So what are support reps instructed to do? Very little, as it turns out. An internal memo dictates that AppleCare does not confirm or deny the presence of malware on a user’s system. Reps are also not to escalate malware-related calls to second level support or refer users to Apple Retail Stores, and it’s made abundantly clear that no attempt to remove the malware be made. That makes sense, of course — why offer to remove something which you can neither confirm or deny is even present on a user’s computer?If a customer has had the presence of mind to call in before actually installing one of the rogue applications or providing his or her admin password, AppleCare can advise that the installation be aborted. Apart from that, the only other advice which can be given is to check for and install updates and browse the Mac App Store or Apple Online Store for available antivirus options.As a technician, I understand Apple’s position here. It’s often hard to determine what exactly a user might be reporting, and declaring a malware infection without being totally certain is a bit like shouting fire in a theater. Apple doesn’t want to needlessly panic users, after all. And I certainly agree with their decision to not attempt removals. Malware cleanup can be a very involved process and should be left to skilled technicians who can see the job through to the bitter end.It does, however, seem as though it’s time for Apple to actually recommend that its users install an antivirus program proactively. Simply tossing one on a system after the fact doesn’t always have the desired effect, and as Mac malware evolves and becomes more sophisticated users will need that extra layer of defense.If you own a Mac and aren’t currently running an antivirus program, you might at least want to check out the one offered by Sophos. It’s light on resources and totally free, and it’s a good way to keep your Mac shiny and malware-free.More at ZD Net
L’homme de l’an 3000 aura les pieds dans l’eauDes chercheurs canadiens ont livré des prévisions plutôt pessimistes concernant les 1.000 prochaines années sur Terre. Au programme, pas mal de catastrophes environnementales…Faire des prévisions pour les 1.000 prochaines années ne relève plus de la science-fiction. Les outils à la disposition des chercheurs permettent en effet de se projeter bien au-delà de notre ère. Une équipe de l’Université de Calgary et du Centre canadien de la modélisation et de l’analyse climatique du ministère de l’Environnement, situé sur le campus de l’Université de Victoria, a eu recours à un modèle mathématique lui permettant de voir la façon dont le monde évoluera d’ici l’an 3000. Et ce n’est pas vraiment beau à voir.Selon les travaux de ces chercheurs canadiens publiés par le magazine Nature Geoscience, de nombreuses zones côtières vont disparaître sous les eaux, faisant diminuer la masse terrestre au profit des mers. Alors que 30% des terres d’Afrique du Nord vont tomber dans la sécheresse, provoquant de grandes famines sur le continent, la partie occidentale de l’Antarctique va fondre. Il y aura néanmoins quelques chanceux dans l’hémisphère Nord qui ne subiront pas d’énormes désagrément, notamment au Canada et en Russie. Si le processus ne peut être arrêté selon Shawn Marshall, professeur de géographie à l’Université de Calgary, il pourrait être freiné en cas de limitation de la production de CO2. Il espère en tout cas que cette étude va éveiller les consciences chez les populations de 2011, afin que celles de l’an 3000 aient quelques chances d’éviter ce scénario catastrophe.Le 12 janvier 2011 à 14:27 • Emmanuel Perrin
In terms of format, the episodes are much shorter (33-45 minutes) than typical Turkish dramas – shorter, for example, than in “Medcezir,” the Turkish adaptation of “The O.C.,” in which you starred previously. Has shooting shorter episodes made a difference for you in terms of your acting style, of the way you get into character?It’s actually way better for me. It means I can really focus and give my character my full energy. It makes me more creative.Netflix has greenlit four seasons, so it looks like ‘The Protector’ is going to be keeping you busy for a while. I’ve heard production schedules for TV series in Turkey can be quite tough. How tough is yours?We are working under more humane conditions than those in most other Turkish TV series. Netflix uses a different production system. We work just 10 hours a day, five days a week. I feel more productive, and so do the other talents and the crew. Typically, each episode in a Turkish TV series is, like, 120-150 minutes long. That means you have to work much harder to wrap up an episode in a week. With this show, a lot is changing in terms of the approach to storytelling, locations, characters and also working conditions. It’s like the rules of the game are being rewritten.Speaking of writing, can you talk to me about the rest of the show’s creative team?I work with three different directors for each season, which has never been done in Turkey before. It seems like a complex system, but it’s actually not. Each director brings their point of view for the episodes they handle, and having different visions makes the show fresher and more varied. In terms of writers, one of them is Jason George [who also serves as executive producer], who did “Narcos.” He has been the “third eye,” as it were, of the show. His global experience and different vision has been immensely helpful. What’s Coming to Netflix in September 2019 ‘Orange Is the New Black’ Creator Jenji Kohan and Star Uzo Aduba Bid Farewell Turkish actor Cagatay Ulusoy plays the titular character in Netflix’s first Turkish original, “The Protector,” currently in production on its third season. His role as young antiques dealer Hakan Demir, who discovers he hails from an ancient line of superheroes and must protect present-day Istanbul from evil forces, marks the first foray into fantasy tropes for a Turkish show.Ulusoy spoke to Variety about how Netflix is disrupting production models and storylines in Turkey’s TV market, which, despite the impact of the country’s economic turbulence, remains among the world’s top five exporters of serial dramas.Why is “The Protector” such a novelty?This series introduces a new genre [of Turkish dramas] to global audiences. It’s a unique mix of fantasy and superhero plot-lines mixed with the elements of social drama and romance that are typical of Turkish TV shows. Instead of a mainstream superhero narrative, it’s more an epic story with a modern hero at its center, but the plot is fast-paced and full of unexpected twists. There is also an element of comedy every now and then to balance the tone. Popular on Variety ×Actors Reveal Their Favorite Disney PrincessesSeveral actors, like Daisy Ridley, Awkwafina, Jeff Goldblum and Gina Rodriguez, reveal their favorite Disney princesses. Rapunzel, Mulan, Ariel,Tiana, Sleeping Beauty and Jasmine all got some love from the Disney stars.More VideosVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9Next UpJennifer Lopez Shares How She Became a Mogul04:350.5x1x1.25×1.5x2xLive00:0002:1502:15 Related
GOG.com is the place to go if you remember playing a game as a kid and would love another playthrough on your modern PC. Chances are, GOG has it available to buy, and not at an extortionate price, either.Today GOG gets even better because the DRM-free games service has kicked off its 2013 #noDRM Summer Sale. The best deal in that sale? Action RPG Torchlight is completely free for the next 48 hours. On top of that, over 500 games are being offered at a discounted price with many of them 50 percent off.Filtering through more than 500 games deciding which ones you want to buy isn’t a quick task, and that’s probably why the #noDRM Summer Sale is set to run until July 5th. You can take your time and cherry pick all the games you want without fear of missing out.It’s hard to actually pick out the highlights in this sale as there quite literally is something for everyone. GOG has split the selection down into bestsellers, action/shooter, adventure, indie, RPG, and strategy/sim categories to try and help, though. Mac gamers haven’t been left out and can pick up such classics as Theme Hospital, Stonekeep, and The Witcher 2 all at 50 percent off. And then there’s the bundle deals with up to 90 percent off.As a regular customer at GOG there is one feature of their system I rely on when such a sale is running — if you login to your account before looking at the long list of games on sale it highlights which titles you already own ensuring there’s no double purchases. A simple, yet very useful feature.
Despite the graphics upgrade, new characters, and tons of additional weapons and items all around, you know exactly what to expect when you fire up the new Super Smash Bros. for the 3DS. The one part of the game that isn’t as obvious — and in fact gives the game a terrific amount of resale value — is Smash Run mode. It’s a ton of fun, and the only thing you should be doing when you aren’t smashing online.It’s one of the most popular games for all of Nintendo’s platforms, and for a good reason. There’s a lot to like about this new installment, including the ability to make your own custom Mii brawler, and smooth online gameplay. The addition of Smash Run changes gameplay enough to where you can enjoy a fresh experience, even if the core mechanics of the Smash are the main focus.Smash Run puts your character in a multi-stage side-scrolling labyrinth full of random enemies from all over the Nintendo universe. As you run through the mission, each kill and treasure chest offers up tools to boost your stats. Each stat boost applies to your character for the duration of the Smash Run, and it resets after the final fight. If you are knocked out at any point during the run, your stats reset and you lose any progress you have gained during the fight. As you are fighting, all of the other players in the Smash Run are playing in separate fights and building up their own stats. At the end of the run, all four of you square off Smash Bros. style and determine the victor.This game mode keeps you from trying to repeat the same three moves over and over again. It takes Super Smash Bros. out of the typical side scrolling fighter and makes it possible for you to focus on character growth, even if only temporarily. The items you pick up along the way can be used for more successful future runs, and it’s the kind of thing that takes the game out of the sort of mindless context the franchise is known for and adds a bit of depth. Of course, you don’t have to play Smash Run at all, but it’s well worth checking out for yourself.
Citation: NOAA study suggests aerosols might be inhibiting global warming (2011, July 22) retrieved 18 August 2019 from https://phys.org/news/2011-07-noaa-aerosols-inhibiting-global.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. The mystery of particles (PhysOrg.com) — A new study led by the U.S, National Oceanic and Atmospheric Administration (NOAA) shows that tiny particles that make their way all the way up into the stratosphere may be offsetting a global rise in temperatures due to carbon emissions. And while scientists cannot yet say with any certainty where exactly the particles are coming from, they are saying that they have confidence that such particles have likely muted global temperature gains by as much as a third of what they would have been. They team, led by John Daniel, a physicist at the NOAA Earth System Research Laboratory (ESRL) in Boulder, CO, has published their results in Science. The surprising aspect of the study is the large amount of aerosols found during a period when there weren’t any giant volcanoes going off, which leads researches to wonder if the aerosols are from the combined effects of multiple small eruptions, or human activity, such as the particles emitted from coal fired power plants, particularly in Asia, where such plants have multiplied in recent years. One thing the research is not able to tell us is what impact aerosols will likely have in the future, because of the uncertainty of their origin, which means there is no way to tell at this point if there will be more, or less of them, which means scientists can only guess if the temperature muting will continue to offset global warming from current and future carbon emissions. Lidar instruments – pointing up from the ground or down from satellites – use reflected light to measure the amounts of particles and their locations, which can influence climate. (Credit: CIRES/NOAA) Sources of aerosols reach the stratosphere from above and below, as shown in the graph. Sulfur dioxide (SO2), carbonyl sulfide (OCS), and dimethyl sulfide(DMS) are the dominant surface emissions which contribute to aerosol formation. (Credit: NOAA) More information: The Persistently Variable “Background” Stratospheric Aerosol Layer and Global Climate Change, Science DOI:10.1126/science.1206027ABSTRACTRecent measurements demonstrate that the “background” stratospheric aerosol layer is persistently variable rather than constant, even in the absence of major volcanic eruptions. Several independent data sets show that stratospheric aerosols increased in abundance since 2000. Near-global satellite aerosol data imply a negative radiative forcing due to stratospheric aerosol changes over this period of about –0.1 W/m2, reducing the recent global warming that would otherwise have occurred. Observations from earlier periods are limited but suggest an additional negative radiative forcing of about –0.1 W/m2 from 1960 to 1990. Climate model projections neglecting these changes would continue to overestimate the radiative forcing and global warming in coming decades if these aerosols remain present at current values or increase. © 2010 PhysOrg.com Explore further The new research has focused on aerosols, the tiny solid or liquid particles that exist in the atmosphere that can affect global temperatures, such as when Mt. Pinatubo in the Philippines, erupted in 1991 causing a worldwide average decrease in temperature of 1 degree Celsius for more than a year. The cooling is not the result of the ash, notes co-author Susan Soloman, but from the sulfur dioxide that is thrust all the way up into the stratosphere, where it oxidizes and adds to the sun reflecting properties of other already existing particles.The team focused on the most recent decade because of the relative absence of massive volcanic eruptions , giving them a more clear environmental view of how much impact minor volcanic eruptions and human activities have on the amount of aerosols in the atmosphere and thus global temperatures. To find out what was going on, they used both ground based data and information from satellites such as Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (Calipso), to measure the amount of aerosols in the atmosphere and at what altitudes.NOAA has released a statement outlining the results of the study, and in it Daniel, says, “stratospheric aerosol increased surprisingly rapidly in that time, almost doubling during the decade,” which forms the basis of the teams conclusions that such aerosols are responsible for the slowdown in increased temperatures that scientist around the world have been expecting due to greenhouse gas emissions.
Growing a business sometimes requires thinking outside the box. Opinions expressed by Entrepreneur contributors are their own. Free Webinar | Sept. 9: The Entrepreneur’s Playbook for Going Global Register Now » Ever find yourself constantly turning on your phone’s screen to check the time or for missed calls, new texts or recent social-media interactions?This not only takes time, but also drains your battery. But two new devices coming to market soon look to address this issue.Smartphone maker LG’s soon-to-be-released G5 will introduce an “Always ON” display feature, in which the time, date and notifications will remain visible on a darkened screen, according to Android Authority. Samsung’s upcoming Galaxy S7 will also include this feature, and the company has filed to trademark the phrase “Always on Display.”Related: Study: Time Spent on Mobile Devices Doubled in 2015While a constant use of an LCD display would drain a battery rather quickly, Geek.com says that the companies are rumored to be changing to AMOLED displays, which are better for battery life because the technology doesn’t rely on a backlight.Engadget points out that the G5 will supposedly be operating the always-on feature as a full-screen version of the LG V10’s smaller second screen, with icons arranged in a line at the top of the screen. It also suggests that Samsung is using more powerful batteries in the Galaxy S7 model to ensure that standby time won’t be too affected by the change.The G5 is expected to hit the market on Feb. 21, the same day Samsung will release more details about the Galaxy S7.Related: Your Future iPhone Might Know How You Are Feeling February 10, 2016 2 min read
Related Content News | Radiation Therapy | August 15, 2019 First Patient Enrolled in World’s Largest Brain Cancer Clinical Trial Henry Ford Cancer Institute is first-in-the-world to enroll a glioblastoma patient in the GBM AGILE Trial (Adaptive… read more An example of retention sutures and treatment balloon in preparation for IORT delivery. 123PreviousNext An example of retention sutures and treatment balloon in preparation for IORT delivery. News | Mammography | August 14, 2019 Imago Systems Announces Collaboration With Mayo Clinic for Breast Imaging Image visualization company Imago Systems announced it has signed a know-how license with Mayo Clinic. The multi-year… read more Assessment of balloon position over the temporary shielding, just prior to closing of retention sutures. Catalyst PT image courtesy of C-RAD News | Patient Positioning Radiation Therapy | August 07, 2019 Qfix kVue One Proton Couch Top Validated by Mevion Medical Systems Qfix and Mevion Medical Systems announced that a special version of the kVue One Proton couch top is now both validated… read more Assessment of balloon position over the temporary shielding, just prior to closing of retention sutures. An actual intraoperative delivery a Xoft unit is attached to a balloon ready for treatment. News | Radiation Therapy | August 16, 2019 Drug Accelerates Blood System’s Recovery After Radiation, Chemotherapy A drug developed by UCLA physician-scientists and chemists speeds up the regeneration of mouse and human blood stem… read more Feature | September 09, 2011 | V. Elayne Arterbery, M.D., MHSA IORT Shows Promise in Early Use A look at techniques and appropriate uses for this emerging radiation therapy for breast cancer Following radiation, the bone marrow shows nearly complete loss of blood cells in mice (left). Mice treated with the PTP-sigma inhibitor displayed rapid recovery of blood cells (purple, right). Credit: UCLA Broad Stem Cell Research Center/Nature Communications Placement of a cavity evaluation device (CED) device through a separate incision in order to determine cavity and final balloon volume. News | PACS | August 09, 2019 Lake Medical Imaging Selects Infinitt for Multi-site RIS/PACS Infinitt North America will be implementing Infinitt RIS (radiology information system)/PACS (picture archiving and… read more Image courtesy of Imago Systems The MD Anderson Proton Therapy Center expansion is expected to be completed in 2023. Rendering courtesy of Stantec. News | Brachytherapy Systems | August 14, 2019 Efficacy of Isoray’s Cesium Blu Showcased in Recent Studies August 14, 2019 — Isoray announced a trio of studies recently reported at scientific meetings and published in medica read more News | Patient Positioning Radiation Therapy | August 15, 2019 Mevion and C-RAD Release Integration for Improved Proton Therapy Treatment Quality Mevion Medical Systems and C-RAD announced the integration between the C-RAD Catalyst PT and the Mevion S250i proton… read more News | Artificial Intelligence | August 13, 2019 Artificial Intelligence Could Yield More Accurate Breast Cancer Diagnoses University of California Los Angeles (UCLA) researchers have developed an artificial intelligence (AI) system that… read more Placement of a cavity evaluation device (CED) device through a separate incision in order to determine cavity and final balloon volume.Intraoperative radiation therapy (IORT) for breast cancer is emerging as a newer alternative to whole-breast radiation therapy and accelerated partial breast irradiation (APBI). The Axxent eBx system from Xoft is a proprietary electronic brachytherapy platform designed to deliver 50 kV radiation, with minimal intraoperative shielding requirements. It becomes a functional and convenient modality for the delivery of intraoperative radiation therapy (IORT).IORT is one method that might offer advantages over conventional APBI techniques. There is the advantage of excellent delineation of the tumor bed under visual control, very good dose distribution and high sparing of the normal tissue. Recent randomized trials showing excellent tumor control have generated new interest in IORT. These advantages were one of the goals of the TARGIT-A Phase III international trial presented in The Lancet in June 2010.The study randomized whole breast radiation therapy in women with invasive ductal carcinoma who were undergoing breast-conserving surgery to intraoperative radiation therapy at the time of breast conserving surgery. This trial presented data that showed equivalent local control and survival, whether patients undergo one fraction of radiation (IORT) or seven weeks of definitive radiation therapy. From a quality-of-life standpoint for patients, this early data suggests excellent cosmetic results and a high degree of patient satisfaction and acceptance.Careful patient selection is key to identifying the group of women that would best benefit from this technique. Selection criteria are very similar to patients who are candidates for APBI. The American Society of Breast Surgeons task force has proposed suitable patients for APBI if several criteria are met: age 45 years or older, tumor size 3 cm or less, an invasive ductal carcinoma, negative margin status at least 2 mm in all directions, and negative sentinel lymph node evaluation.The TARGIT trial accepted women with early breast cancer if they were age 45 years or older and had undergone wide local excision for invasive ductal carcinoma. When looking at the characteristics of the tumors in the patients in the international trial, the median age was 63 years, 86 percent of the tumors were smaller than 2 cm, 90 percent expressed estrogen receptors and nodes were uninvolved in 83 percent of patients.The IORT Technique, Play-by-PlayIn our experience, sentinel lymph node dissection (SLND) with frozen section diagnosis is performed at the time of the partial mastectomy and the planned IORT treatment for all invasive cancers. Noninvasive cancers have SLND at the discretion of the surgeon. Patients with positive sentinel lymph nodes on frozen section are ineligible for IORT and are treated with conventional radiation.The patients undergo a standard partial mastectomy; however, the tissue dissection is carried down to the level of the pec fascia. Blunt dissection is performed circumferentially in order to accommodate a chest wall shield placed temporarily into the cavity for the duration of radiation to protect the chest wall from radiation damage. The diameter of the circular chest wall shielding is customized to 1 cm larger than the actual treatment balloon diameter. The goal of the temporary lead shielding is to protect the underlying heart, ribs and lung from the high dose of radiation delivered.One of the issues with IORT is the inability to obtain margin assessment prior to delivery of the radiation. Margin assessment is performed by the pathologist in a standard fashion. In the event of a positive margin, patients are re-excised. If the re-excision is positive, patients are offered traditional radiation over five weeks, or if chemotherapy is indicated, an accelerated regimen over 16 days. In the TARGIT trial, 85 percent of patients received IORT alone and did not require additional external beam radiation.A cavity evaluation device (CED) is placed through a separate incision and filled to a desired predetermined volume, based on the partial mastectomy cavity size. Because of the intraoperative and real-time nature of the radiation delivery, the radiation plans are already pre-planned for a variety of treatment balloon sizes at 5 cc increments, based on balloon sizes from 30 cc up to 70 cc. The dose of radiation delivered is 2,000 cGy prescribed to the surface of the balloon. Once the cavity volume is determined in appropriate size using the CED, the actual treatment balloon is exchanged and placed into the cavity.In order to temporarily close the partial mastectomy cavity, retention-type sutures are used to close the skin around the balloon. The sutures also are used to build up the subcutaneous tissue in order to increase the balloon-to-skin distance.In order to safely deliver the radiation and reduce the risk of skin complications, the distance from the balloon surface and the skin surface should be at least 1 cm. Intraoperative ultrasound is utilized to determine this prior to initiating treatment. A second timeout is performed with the radiation and operating room teams prior to starting the radiation beam.At this point, the radiation source is inserted into the balloon and radiation is initiated. The typical treatment time is eight to 10 minutes, depending on the balloon size. The overall treatment time of the radiation oncology team is approximately 22 minutes, and the whole IORT procedure only adds 25-30 minutes of additional total operative time.Key personnel are in the room during the actual treatment delivery and are wearing lead aprons, thyroid shielding and conventional shielding during the radiation delivery, similar to what would be used for fluoroscopy. After radiation is delivered, the balloon is deflated and removed, the temporary shielding is removed and the surgical site is closed in a standard fashion.Postoperatively, both the breast surgeon and radiation oncologist typically see patients at one month, six months and every six months thereafter.Initial Challenges and After-EffectsWe initially had some difficulty with the Flexi Shield Mini chest wall shielding marketed by Xoft, because the deposition of tungsten particles led to tungsten deposition seen on postoperative mammograms. This happened in two of our four patients. In the other patients, we switched to a lead-based shielding and we had no further issues with any post-mammography particles seen from the lead shielding.The tungsten deposition was seen on post-mammographic images at two months following radiation treatment and had the particulate appearance, according to the radiologist, similar to deodorant particles on the mammogram. Neither patient required any surgical intervention, as the media and literature had reported this finding and it was not a complete surprise to our participating radiologist.From a clinical standpoint, the amount of tungsten deposition did not interfere with future imaging, and certainly in our cases, according to the radiologist at our institution, could not be confused with malignant calcifications. The tungsten deposition covered an area just close to the chest wall, approximately 5 to 7 cm in the exact areas where the temporary shield had been placed during treatment.The Axxent Flexi Shield Mini is an optional accessory device for IORT and is one of several shields available. The issues with the Flexi Shield eventually led to iCAD initiating a voluntary recall of the device. iCAD Inc., the parent company of Xoft, is actively addressing the situation, working closely with physician customers, impacted patients and the U.S. Food and Drug Administration (FDA). In fact, iCAD recently received clearance from the FDA for its new Axxent Rigid Shield, a stainless steel shielding device to protect tissue and/or organs from X-ray radiation.Final CommentsIORT is emerging as an alternative to whole breast radiation therapy and outpatient APBI in a select group of women with early stage breast cancer. It is an increasingly attractive choice, offering several benefits to both patients and physicians.From the oncologic perspective, radiation is delivered to the lumpectomy cavity as soon as the tumor is removed, before any remaining cells have a chance to reproduce. Balloon placement and tailoring of this cavity decreases the ability of geographic miss, in which the prescribed radiation dose is inaccurately delivered to the tumor bed. Moreover, in very superficially located tumors that are otherwise not amenable to APBI or without multi-channel balloon or cavity-based techniques, the use of intraoperative-placed temporary retention sutures allows the surgeon to create an adequate skin-to-balloon distance needed for safe dose delivery.From a patient perspective, the extra 20 to 30 minutes spent by the surgeon and radiation oncologist will often negate the logistically impossible six-week or five-day requirement of whole breast radiation therapy or APBI. The use of IORT will obviate the need for mastectomy in patients who cannot travel to a radiation treatment center, which may be a significant advantage in Third World and developing countries where travel precludes patients opting for breast conservation.When compared with other techniques, IORT is emerging as a valid patient- and physician-friendly alternative. With our initial patient experience, overall results were extremely encouraging, with patients achieving excellent cosmesis and high levels of satisfaction. As the variety of treatment options for breast cancer emerge, IORT promises excellent tumor control, cost containment and the possibility of widespread adoption. V. Elayne Arterbery, M.D., MHSA, is currently clinical chief of radiation oncology at Crittenton Cancer Center in Rochester, Mich., and was a clinical instructor at the Johns Hopkins Oncology Center in Baltimore, Md. A graduate of Stanford University, Arterbery is well-known among her colleagues in the field of radiation oncology worldwide. For questions, contact Dr. Arterbery at (248) 844-4025 or email@example.com (link sends e-mail). References:1 Vaidya JS, Joseph DJ, Tobias JS, Bulsara M, Wenz F, Saunders C, Alvarado M, Flyger HL, Massarut S, Eiermann W, Keshtgar M, Dewar J, Kraus-Tiefenbacher U, Sutterlin M, Esserman L, Holtveg HMR, Roncadin M, Pigorsch S, Metaxas M, Falzon M, Matthews A, Corica T, Williams NR, Baum M. “Targited intra-operative radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomized, non-inferiority trial Phase III.” The Lancet, 2010; published online June 5, 2010, pp. 1-12. FacebookTwitterLinkedInPrint分享 News | Proton Therapy | August 08, 2019 MD Anderson to Expand Proton Therapy Center The University of Texas MD Anderson Cancer Center unveiled plans to expand its Proton Therapy Center during a… read more News | Proton Therapy | August 06, 2019 IBA Signs Contract to Install Proton Therapy Center in Kansas IBA (Ion Beam Applications S.A.) recently signed a contract and received the first payment for a Proteus One solution… read more
News | Enterprise Imaging | July 29, 2019 Philips Announces 10-year Enterprise Informatics Agreement With Centre Hospitalier Régional Universitaire de Nancy Philips and Centre Hospitalier Régional Universitaire (CHRU) de Nancy, a leading academic hospital in the Grand Est… read more Feature | Information Technology | June 27, 2019 | By Greg Freiherr Smart Algorithm Extracts Data from Radiology Reports Radiology reports may contain information essential to figuring out a patient’s condition. read more News | PACS | June 26, 2019 Mini-PACS Solution for Image Management and Workflow Optimization ImageGrid Mini is a feature-rich, reliable and cost-effective image management and workflow optimization solution, pr read more Related Content News | PACS | August 08, 2019 NetDirector Launches Cloud-based PDF to DICOM Conversion Service NetDirector, a cloud-based data exchange and integration platform, has diversified their radiology automation options… read more News | Information Technology | July 01, 2015 Carestream Demonstrates Vue PACS With Native Reporting Feature at ISCT Workstation Face-Off Module inserts interactive hyperlinks to images or tables directly into radiology reports News | PACS | August 09, 2019 Lake Medical Imaging Selects Infinitt for Multi-site RIS/PACS Infinitt North America will be implementing Infinitt RIS (radiology information system)/PACS (picture archiving and… read more News | Enterprise Imaging | June 27, 2019 Ambra Health Announces Integration With Box Ambra Health announced an integration with Box to enable the sharing of medical imaging directly from within Box’s… read more News | Cardiovascular Ultrasound | July 02, 2019 Konica Minolta Healthcare Partners With DiA Imaging Analysis for AI-based Cardiac Ultrasound Analysis DiA Imaging Analysis has partnered with Konica Minolta Healthcare Americas Inc. to expand analysis capabilities of… read more Technology | Enterprise Imaging | July 05, 2019 Hyland Healthcare Adds ImageNext Imaging Workflow Optimizer to Enterprise Imaging Suite Hyland Healthcare is launching ImageNext, a vendor-neutral imaging workflow optimizer that combines intelligent imaging… read more News | PACS | July 02, 2019 Laurel Bridge and 3M M*Modal Partner to Improve DICOM Structured Reporting July 2, 2019 — Laurel Bridge Software announced an expanded relationship with 3M M*Modal, a provider of clinical docu read more Technology | Cybersecurity | August 07, 2019 ScImage Introduces PICOM ModalityGuard for Cybersecurity ScImage Inc. is bridging the gap between security and functionality with the introduction of the PICOM ModalityGuard…. read more July 1, 2015 – Carestream showcased the Carestream Vue PACS (picture archiving and communication system) workstation with streamlined reading, processing and reporting of imaging studies at the “Workstation Face-Off,” part of the annual International Symposium on Multidetector-Row CT. The event, held recently in San Francisco, was hosted by the International Society of Computed Tomography (ISCT).Competitors were challenged to demonstrate how workstations can augment diagnosis and communication with clinicians and patients. Carestream was able to demonstrate how its unified backend architecture, coupled with automated 3-D processing and interactive reporting, improves the interpretation process, data exchange and collaboration between radiology stakeholders.Carestream offers a PACS workstation that can complete all cases at the annual Workstation Face-Off. This year’s cases included: carotid stenosis versus occlusion; chest aortic coarctation; cirrhosis; radial artery occlusion; and sigmoid volvulus.This year the radiologist reading exams on the Vue PACS workstation used Carestream’s newest native Vue Reporting module. The module inserts interactive hyperlinks to images or tables that display key anatomical features directly from the report. Physicians view Carestream’s latest version of Vue Reporting as an improvement over traditional text-only radiology reporting. Most indicate they would prefer to refer patients and peers to facilities that adopt interactive, user-friendly reporting practices, according to “Traditional Text-Only vs. Multimedia Enhanced Radiology Reporting (MERR): Referring Physicians’ Perceptions of Value” presented at the 2014 Radiological Society of North America conference.Throughout the cases, Carestream’s Vue Reporting, Vue Motion and My Vue boosted productivity by simplifying the collaboration and data exchange workflow.Radiologist Orly Goitein, M.D., from Sheba Medical Center in Israel, presented cases for Carestream at the event.For more information: www.carestream.com FacebookTwitterLinkedInPrint分享
Ex-FBI agent details raid on Phoenix body donation facility LONDON (AP) — Flags flew at half-staff around Ireland and the country’s parliament suspended normal business Wednesday as the nation mourned six students killed when a balcony collapsed during a party in Berkeley, California.Prime Minister Enda Kenny offered a message of sympathy, and books of condolences were opened at University College Dublin, where three of the students studied. Tributes were paid to the students, who were among 700 Irish students in the San Francisco Bay Area for the summer. ___OLIVIA BURKEBurke, 21, was expected back at the Dun Laoghaire Institute of Art, Design and Technology in September to start her final year of a degree in entrepreneurship and management.Annie Doona, the institute’s president, said Burke was working at a sushi restaurant and sharing an apartment with some of the others killed and injured in the Berkeley balcony collapse.“She was doing very well, and enjoying herself and making great friends,” Doona said. “It’s terribly sad.”The school was providing psychological support for students on the campus, she said.“Although the students have finished, we think that some of them will come here. They’ll want to meet, they’ll want to hug, they’ll want to talk about Olivia, and they’ll want to spend a bit of time just thinking about her and grieving,” Doona said.___EOGHAN CULLIGANCulligan had finished his third year at the Dublin Institute of Technology, where he was studying logistics and supply chain management.Ballyboden St. Enda’s — the club where he played Gaelic football — posted a tribute to him.“Eoghan was very popular with his teammates and this tragic news is keenly felt by all members of our club, but especially by those players and mentors who knew him well,” the club said. “We would like to extend our deepest sympathy to his parents Gerry & Marie and to his brothers Stephen & Andrew and to all the extended Culligan family.” ___ASHLEY DONOHUEIrish-American Donohue, 22, was a first cousin of Burke and student at Sonoma State University north of San Francisco.Josh Wilson, assistant principal at Rancho Cotate High School, remembers Donohoe as a cheerful person and skilled soccer player who returned after graduating to help coach the school soccer team.“She absolutely was well-received and well-liked not only by her peers but the faculty at Rancho Cotate,” he said.“She just always had a smile on her face and transcended peer groups and cliques and had a friend in just about every social circle.”___LORCAN MILLERMiller was studying medicine at University College Dublin. At his high school, St. Andrew’s College in Booterstown, south Dublin, headmaster Peter Fraser recalled Miller as a “positive, engaging, decent boy who was incredibly talented, but normal, modest and balanced about it all.”Miller played on the school hockey team, sang in the choir, performed in musicals and took part in the school’s Model United Nations.“He was hugely popular,” Fraser said.___NICCOLAI SCHUSTERSchuster, 21, was studying at University College Dublin and had been a student at St. Mary’s College in the Rathmines district near the Irish capital. In 2010, he took part in the Ghana Immersion Project, which sends young people to the West African country, where they attend school with local students and help primary school students learn English. Check your body, save your life Sponsored Stories Here’s how to repair and patch damaged drywall A flag of Ireland is draped over wreaths at the Library Gardens apartment complex in Berkeley, Calif., Tuesday, June 16, 2015. Berkeley police say several people are dead and others injured after a balcony fell shortly before 1 a.m., near the University of California, Berkeley. (AP Photo/Jeff Chiu) Comments Share Parents, stop beating yourself up New Valley school lets students pick career-path academies ErrorOK ErrorOK Top Stories Clean energy: Why it matters for Arizona ___EIMEAR WALSHWalsh, a medical student at UCD, was a high school classmate of Burke at Loreto College in Foxrock, south Dublin.The principal at Loreto described the two girls as smart and beautiful.“They were in the prime of their lives,” principal Bernadette Prendiville said. “They had a successful time in school, went about their work quietly and had everything going for them, everything ahead of them.”The Church of Our Lady of Perpetual Succour in Foxrock held a vigil Tuesday in the aftermath of the tragedy. Parish priest Frank Herron, who knows the Walsh family, told The Associated Press that the community is shocked and the family is distraught.“She was very intelligent and had so much to offer,” he said. “She really looked forward to going to the States with her friends and spending her summer there working and having time to be together. The community here felt very empty, so we opened up the church. We had a huge reaction of support and solidarity.”Copyright © The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed. Milstead says best way to stop wrong-way incidents is driving sober
Budget hotel aggregator, OYO, backed by SoftBank is planning to double its inventory of 70,000 rooms to 1.5 lakh by the end of next year to cater to growing business and leisure travel in the country. It will add between 10,000 and 20,000 rooms this year.“We have been doubling our revenues year-on-year and within this year we will continue to grow our revenues by two-and-a-half times year-on-year. We will see more properties coming up in areas where occupancy rates are high,” said Ritesh Agarwal, Founder, OYO.The company’s gross bookings run rate grew to Rs 2,563 crore annually. “Last year in March, we announced that we had gotten into a net transaction profit, which means that for every Rs 100 we sell, we were making more than Rs 100. Our gross margin has been 25% and net margin is at 16%. Our belief is that in the hospitality space, long-term repeats play the biggest role,” Agarwal said.OYO is working on making bookings easier for customers and will provide more details of its properties. Each property will be given a unique number to distinguish it from neighbouring OYO properties and the signages are expected to display the address more clearly. More local residents will be allowed to use OYO as there was growing demand for this facility for various reasons.
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